Nutriprem range

Importance of milk fat

Breast milk has a specific fatty acid profile containing high levels of ß-palmitate (palmitic acid in the ß-position). When palmitic acid is in the ß-position, fats are metabolised more efficiently by infants¹².

This provides beneficial effects for the infant, including^4-8:

• Easier digestion
• Softer stools
• Better fat absorption
• Improved calcium absorption 

Nutriprem 1, hydrolysed nutriprem and nutriprem 2 contain milk fat, which is naturally rich in ß-palmitate. 

Prebiotic Oligosaccharides (OS) improve gut health

One of the major differences between breastfed and formula-fed infants is the development of the intestinal flora.¹³

Non-digestible oligosaccharides that act like prebiotics in breast milk play an important role in the production of beneficial bacteria supporting gut intestinal flora development.¹⁴

Nutriprem 1 and nutriprem 2 are the only preterm products that contain a blend of prebiotic OS, which is proven to:

• Increase beneficial bifidobacteria¹
• Decrease potentially pathogenic bacteria²
• Reduce gastrointestinal transit time³
• Decrease stool viscosity, resulting in softer stools³
• Potentially improve enteral tolerance in very preterm infants¹⁵

1. Boehm G et al. Arch Dis Child Fetal Neonatal Ed 2002;86:F178-81.
2. Knol J et al. Acta Paediatr 2005;94(449):31-3.
3. Mihatsch W et al. Acta Paediatr 2006;95(7):843-8.
4. Bar-Yoseph F et al. Prostaglandins Leukot. Essent. Fatty Acids 2013;89(4):139-43.
5. Carnielli et al Am J Clin Nutr 1995;61(5):1037-1042.
6. Carnielli et al. J Pediatr Gastroenterol Nutr 1996;23(5):553-560.
7. Kennedy et al. Am J Clin Nutr 1999;70(5):920-7.
8. Quinlan et al. Pediatr Gastroenterol Nutr 1995;20(1):81-90.
9. Agostoni C et al. J Pediatr Gastroenterol Nutr. 2010;50(1):85–91.
10.  Aggett P et al. J Pediatr Gastroenterol Nutr. 2006;42(5):596–603.
11.  Doherty et al. Front Pediatr. 2018;20:6:91.
12.  Innis S et al. Lipids. 1994;29(8):541–5.
13.  Harmsen HJM et al. J Pediatr Gastroenterol Nutr 2000;30(1):61–7
14. Groer MW, et al. Microbiome 2014;2:(38):1-8
15. Modi N et al. Pediatr Res. 2010;68(5):440–5.