Aptamil Comfort's ingredients, clinical evidence, parent and Healthcare Professional feedback
IMPORTANT NOTICE: Breastfeeding is best. Aptamil Comfort is a food for special medical purposes for the dietary management of colic & constipation. It should only be used under medical supervision, after full consideration of the feeding options available including breastfeeding. Suitable for use as the sole source of nutrition for infants from birth and as part of a balanced diet from 6-12 months. Refer to label for details.
Tailored fat blend with high levels of beta-palmitate may help to promote softer stools and aid the absorption of fat and calcium1–3
Partially hydrolysed whey protein for easy digestion and reduced gastrointestinal transit time4,5
Prebiotic oligosaccharides – short chain Galacto-oligosaccharides and long chain Fructo-oligosaccharides (scGOS:lcFOS) (9:1) supports a healthy gut microbiota by increasing the number of beneficial bacteria and reducing harmful bacteria6,7
Reduced lactose can help to reduce flatulence and abdominal discomfort8
|Reference||Study design & population||Groups||Study period||Outcomes (Comfort vs. control)|
|Veitl et al. 2000||RCT with infants < 3 month with at least one of the following symptoms: excessive crying, constipation (with or without cramps), and general abdominal distress||Comfort (n=34) Control (n=17)||2 weeks||
|Schmelzle et al. 2003||RCT with healthy term infants < 2 weeks||Comfort (n=49) Control (n=53)||10 weeks||
|Savino et al. 2003||Prospective observational study with infants < 3 months infantile colic and/or constipation||Comfort (n=604)||2 weeks||
|Savino et al. 2005||RCT with infants < 4 months with infantile colic||Comfort (n=55) Control (n=40)||2 weeks||
|Savino et al. 2006||RCT with infants < 4 months with infantile colic||Comfort (n=103) Control (n=93)||2 weeks||
|Bongers et al. 2007||RCT (cross-over design) with infants 3-10 weeks with constipation||Comfort (n=38) Control (n=38)||6 weeks||
*based on an observational study conducted in Italy, with 604 infants. Adapted from Savino et al. 2003
- Havlicekova Z et al. Nutr J. 2016;15:28.
- Carnielli VP et al. Am J Clin Nutr. 1995;61:1037–1042.
- Kennedy K et al. The American Journal of Clinical Nutrition. 1999;70.5: 920–927.
- Billeaud C et al. Eur J Clin Nutr. 1990;44(8):577–583.
- Tolia V et al. J Pediatr Gastroenterol Nutr. 1992;15(3):297–301.
- Knol J et al. J Pediatr Gastroenterol Nutr. 2005;40(1):36–42.
- Moro G et al. J Pediatr Gastroenterol Nutr. 2002; 34(3):291–295.
- Kanabar D et al. J Hum Nutr Diet. 2001;14:359–363.
- Veitl et al. Ernährungsmed. 2000;2:14–20.
- Schmelzle H et al. J Pediatr Gastroenterol Nutr. 2003;36(3):343–351.
- Savino et al. Acta Paediatr Suppl. 2003;91:86–90.
- Savino et al. Acta Paediatr Suppl. 2005;94:120–124.
- Savino F et al. Eur J Clin Nutr. 2006;60:1304–1310.
- Bongers et al. Nutr J. 2007;6:8.
- Scholtens PA et al. World J Gastroenterol. 2014;20(37):13446–13452.