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The Aptamil range

Inspired by 40 years of research in early life science, we continually innovate our range of Aptamil formula milks, including Aptamil with PronutraTM-ADVANCE and Aptamil Advanced. These formulations contain ingredients such as prebiotic oligosaccharides, lipids and postbiotics which have been shown to support the normal development of a healthy immune system1-3

Immunity molecules


Changes to Aptamil Infant, Follow On and Toddler milks packaging and formulation Download here

Which formula milk ingredients support normal immune development?

We continue to innovate our formulations inspired by breastmilk research, although it is not possible to replicate the unique and valuable antibodies that breastmilk provides.  Aptamil formula milks, including Aptamil Advanced and Aptamil with Pronutra Advance contain varying combinations of the ingredients listed next to this paragraph. These ingredients are shown to support normal immune system development1-3.

  • Direct effect on immune cells1,
  • Block and reduce infections 2
  • Suppress pathogens and harmful bacteria5,6
  • Support normal brain development3
  • Omega-6 Arachidonic Acid (AA) and Omega-3 Docosahexaenoic Acid (DHA) in 1:1 ratio similar to breastmilk7,8
  • Improved neurodevelopment compared to DHA alone9,10
  • Moderate inflammatory responses11
  • Support normal immune system development12
  • Reduce severity of Gastrointestinal infections13
  • Increasing the antibody response to pathogens14
  • Positive influence on gut barrier function15
  • Modulate the gut microbiota14

Aptamil Product Range

First Infant Milks

Aptamil First Infant Milk and Aptamil Advanced First Infant Milk are suitable from birth for combination or bottle feeding.


Follow On Milks

Aptamil Follow On Milks are suitable from 6 months as part of a weaning diet.


Toddler Milks

For toddlers over 1 year of age, specially formulated with our blend of GOS/FOS plus iron. Also containing vitamin D which contributes to the normal function of the immune system.


Breastfeeding is best. Infant milk is suitable from birth when babies are not breastfed. Follow-on milk is only for babies over 6 months, as part of a mixed diet and should not be used as a breastmilk substitute before 6 months. We advise that the use of formula milks and the decision to start weaning should be made only on the advice of a doctor, dietitian, pharmacist or other professional responsible for maternal and child care based on baby’s individual needs. Use Growing Up milk as part of a varied, balanced diet from 1 year.

1. Eiwegger T, et al. Pediatr Res, 2004;56(4):536-40

2. Eiwegger T, et al. Pediatr Allergy Immunol, 2010;21(8):1179-88

3. Wang S, et al. Neuroscience and biobehavioral reviews. 2018;95: 191-201

4. Simon AK, Hollander GA, McMichael A. Proc Biol Sci. 2015;282(1821):20143085

5. Jackson KM, Nazar AM. J Am Osteopath Assoc 2006;106(4):203–207.

6. Knol J et al. Acta Paediatr Suppl 2005;94(449):31-3

7. Knol J et al. J Paediatr Gastroenterol Nutr 2003;36566.32

8. Brenna et al. Am J Clin Nutr 2007. 85: 1457

9. Zou L et al. Annu Rev Food Sci Technol 2016. 7: 139

10. Hadley et al. Nutrients 2016. 8: 216

11. Brenna et al. Nutr Rev 2016. 74: 329

12. Calder PC. Nutrients 2010;2(3):355–374

13. Carlson SE, Colombo J. Adv Pediatr. 2016;63(1):453-471

14. Thibault H et al. J Pediatr Gastroenterol Nutr 2004;39(2):147-52

15. Mullié C, Yazourh A, Thibault H et al. Pediatr Res 2004;56: 791–795

16. Tsilingiri K, Rescigno M. Benef Microbe 2013;4(1): 101–107

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