We are not supporting this browser

A topic in 10 questions: Weaning the child with Cow's Milk Allergy

Allergy expert Dr Carina Venter offers advice on weaning infants with Cow's Milk Allergy.

Please log in to access this content

Simply log in or register to Nutricia Academy today to access this content as well as a host of other trusted education resources.


Cow's Milk Allergy (CMA) is characterised by an immunological response to the protein(s) in cow’s milk. Symptoms can appear immediately after eating (IgE-mediated) or a few hours later (non-IgE-mediated). Some healthcare professionals use the term cow's milk protein intolerance to refer to non-IgE-mediated CMA, which wrongly gives the impression that the immune system is not involved. The only intolerance to cow’s milk is lactose intolerance – a reduced ability, or in rare cases inability, to digest the sugar (lactose) in milk. It is difficult to estimate how serious the problem of CMA is worldwide as there may be ‘pockets’ of high and low prevalence. An estimated 2.0–2.5% of UK children aged 0 to three years suffer from CMA, the majority showing signs of non-IgE-mediated CMA1.

Q2 What first foods are suitable for children with CMA?

Although weaning guidelines exist for infants in general3, and for infants at high risk of developing allergic disease, there are no official guidelines on weaning infants with CA. Experts agree that for children with existing allergies, foods should be introduced individually, a few days apart, and weaning should commence with low allergenic foods (e.g. apple, pear, butternut squash, courgette). The DH also recommends that these infants, as well as those at high risk of developing food allergies, avoid highly allergenic foods (e.g. eggs, fish and nuts) until six months of age4. National levels of allergies should also be considered when devising weaning diets as these can vary between countries5.

Q3 What advice can be given to parents to help them avoid cows’ milk in their infant’s diet when purchasing food?

Many foods that don’t list milk within the ingredient list still say “may contain milk due to the processing method” on the packaging. Very few children have to avoid these products, and a consultation with a dietitian is recommended to determine whether an infant needs to avoid cows’ milk completely, including “trace amounts”, or is able to tolerate foods containing a small amount6. This information is crucial as under-restriction may lead to ongoing/severe symptoms and over-restriction may impact food intake and nutritional status. Terms that indicate a product contains milk (e.g. casein, whey, lactose, cream, non-fat milk solids, etc.) will be discussed during the consultation, and a diet sheet on foods to avoid, foods to consume (e.g. those in supermarket “free from” ranges), reading labels and weaning will also be provided by the dietitian.

Q4 What advice can be given to parents on avoiding cows’ milk when preparing food in the home?

Preparing cows’ milk free foods at home is a more affordable and easier way of providing a cow’s milk-free diet than checking food labels when purchasing food. Parents can use ‘allergy-free’ cookbooks or ask dieticians for help modify recipes. Most companies producing hypoallergenic infant formula now provide recipe/weaning booklets for parents.

Q5 Are there any specific nutritional concerns for breastfed infants with CMA, and how should these be addressed?

Breastfeeding mothers avoiding cows’ milk from their diet should take a daily supplement of 1000mg calcium in combination with calcium-fortified milk alternatives, and their diet should be assessed for other nutrients of concern, particularly iodine7. There is currently concern about vitamin D intake with reference to allergies in particular, and NICE recommends that women take 10μg vitamin D per day during pregnancy and while breastfeeding8. It is also important that breastfed infants commence vitamin D supplementation from six months of age, or from one month if the mother did not take vitamin D during pregnancy8.

Q6 Are there any specific nutritional concerns for formula-fed infants with CMA and how should these be addressed?

Children and infants with CMA should be fed hypoallergenic formula of which there are two types: extensively hydrolysed formulas (based on cows’ milk but the proteins are broken down to an extent where they will not cause allergic reactions in most infants), and amino acid formulas, which should be tolerated even by those with severe CMA9. Using a suitable hypoallergenic formula should minimise any effect on total nutrient intake. However, this depends on infants consuming a sufficient amount of formula – a particular problem in children with CMA as some formulas may not be particularly palatable10. NICE8, in line with the DH, recommends that infants over six months who consume less than 500ml (1 pint) of formula milk per day take vitamin drops containing vitamins A and D (RNI 7μg/day).

Calcium and iron intake should also be assessed, taking into account food and formula intake. CMA infants aged six months and over may benefit from moving on to a Stage 2 hypoallergenic formula (where available) with added nutrients, specifically designed for their age group. Healthcare professionals should familiarise themselves with the nutrient profile of hypoallergenic formulas designed for children aged six months plus, particularly in terms of calcium, vitamin D and iron content (often lacking in the diets of food allergic children)6.

Q7 Are there any challenges in introducing different tastes and textures into the diet of an infant with CMA?

Introducing new tastes and textures in an infant with CMA plays as important a role in preventing fussy eating behaviour as it does for any infant undergoing weaning11. This can be problematic in CMA infants, as alternatives for many everyday foods (e.g. yoghurt, fromage frais, cream cheese, macaroni cheese) can be difficult to find. Although some children with CMA may tolerate soya yoghurts, they may not be suitable for 30-50% of CMA cases.

Q8 How should the nutritional status of the child be monitored?

Infants should be weighed regularly by their health visitor and plotted on the UK-WHO growth charts. Length should also be measured, as children with CMA can suffer from stunted growth12. A paediatrician or paediatric allergist should be contacted if there are any concerns.

Q9 How and when should the child with CMA be screened for other potential food allergies?

Despite the publication of three allergy guidelines13-15, practices vary across the UK and the world. There are two schools of thought:

Testing children with IgE-mediated CMA for other foods will only indicate sensitisation. Without doing food challenges in these children (another clinical dilemma in itself), this can lead to unnecessary dietary restriction.

It is known that children with CMA are more likely to develop other food allergies, and not testing children with CMA for these may lead to other severe allergic reactions at home.

Weaning children with non-IgE-mediated CMA has not been formally studied and it makes sense to trial other allergenic foods in those children with less severe symptoms. Those with more severe non-IgE-mediated allergies should be given secondary or tertiary care to obtain more specific advice.

Q10 What practical advice can be given to parents about introducing other allergenic foods?

Introduce only one new food at a time and start with foods that are known to be tolerated by the child, ideally cooked. Introduce new foods earlier during the day, observe the infant for possible allergic reactions and be clear on how to deal with allergic reactions, as directed by the healthcare professional16.

  1. Venter C, Pereira B, Voigt K et al. Prevalence and cumulative incidence of food hypersensitivity in the first 3 years of life. Allergy 2008;63(3):354-359.
  2. Agostoni C, Decsi T, Fewtrell M et al. Complementary feeding: a commentary by the ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr 2008;46(1):99-110.
  3. British Dietetic Association. BDA Paediatric Group Position Statement: Weaning infants onto solid foods. 2010. http://www.bda.uk.com/publications/statements/PositionStatementWeaning.pdf [Accessed Mar 2012]
  4. Department of Health. Weaning: starting solid foods. 2007. http://www.dh.gov.uk/prod_consum_dh/groups/ dh_digitalassets/documents/digitalasset/dh_084164.pdf [Accessed Mar 2012]
  5. Andersen MB, Hall S, Dragsted LO. Identification of European allergy patterns to the allergen families PR-10, LTP, and profilin from Rosaceae fruits. Clin Rev Allergy Immunol 2011; 41(1): 4-19
  6. Venter C, Meyer R. Session 1: Allergic disease: The challenges of managing food hypersensitivity. Proc Nutr Soc 2010;69(1):11-24.
  7. Pearce EN. Iodine nutrition in the UK: what went wrong? Lancet 2011;377(9782):1979-1980.
  8. National Institute for Health and Clinical Excellence (NICE). Clinical Guideline 11. Improving the nutrition of pregnant and breastfeeding mothers and children in low-income households. 2008. http://www.nice.org.uk/nicemedia/ live/11943/40097/40097.pdf [Accessed Mar 2012]
  9. Høst A, Koletzko B, Dreborg S et al. Dietary products used in infants for treatment and prevention of food allergy. Joint Statement of the European Society for Paediatric Allergology and Clinical Immunology (ESPACI) Committee on Hypoallergenic Formulas and the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Committee on Nutrition. Arch Dis Child 1999;81(1):80-84.
  10. Mennella JA, Forestell CA, Morgan LK et al. Early milk feeding influences taste acceptance and liking during infancy. Am J Clin Nutr 2009;90(3):780S-788S.
  11. Northstone K, Emmett P, Nethersole F; ALSPAC Study Team. The effect of age of introduction to lumpy solids on foods eaten and reported feeding difficulties at 6 and 15 months. J Hum Nutr Diet 2001;14(1):43-54.
  12. Vieira MC, Morais MB, Spolidoro JV et al. A survey on clinical presentation and nutritional status of infants with suspected cow’s milk allergy. BMC Pediatr 2010;10(1):25.
  13. Fiocchi A, Brozek J, Schünemann H et al. World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow’s Milk Allergy (DRACMA) Guidelines. Pediatr Allergy Immunol 2010; 21 Suppl 21:1-125
  14. Boyce JA, Assa’ad A, Burks AW et al. Guidelines for the Diagnosis and Management of Food Allergy in the United States: Report of the NIAID-sponsored Expert Panel. J Allergy Clin Immunol 2010;126(6 Suppl):S1-58.
  15. National Institute for Health and Clinical Excellence (NICE). Diagnosis and assessment of food allergy in children and young people in primary care and community settings. 2011. http://guidance.nice.org.uk/CG116/Guidance [Accessed Mar 2012]
  16. NHS Choices. Food allergy. 2012. http://www.nhs.uk/conditions/food-allergy/Pages/Intro1.aspx [Accessed Mar 2012]

You may also be interested in

Paediatric Cow's Milk Allergy (CMA): Common challenges in primary care

Recorded webinars & presentations | Cow's Milk Allergy
54 mins

The Role of Psychology in Optimal Management: Addressing Gaps in UK Services

Recorded webinars & presentations | Cow's Milk Allergy
54 mins




Create a new account I've forgotten my password

Nutricia uses cookies on this website. With your consent we will use them to measure and analyze usage of the website (analytical cookies), to tailor it to your interests (personalisational cookies), and to present you relevant advertising and information (targeting cookies). For more information please read the cookie policy.

Privacy Settings

You can choose your preferences anytime for cookies and tracking. For more information please read our cookie policy.

  • Strictly necessary

    They are necessary for the website to function and cannot be switched off. They are usually only set in response to actions made by you which amount to a request for services (setting your privacy preferences, logging in, filling in forms, etc.). You can set your browser to block or alert you about these cookies, but some parts of the site will not then work.

  • Analytical cookies

    They allow us to count visits and traffic sources, to measure and improve the performance of our site. They show us which pages are the most and least popular and how visitors move around the site. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance.

  • Personalisation cookies

    They enable website’s enhanced functionality and personalisation. They may be set by us or by third parties whose services we have added to our pages. If you do not allow these cookies, some or all of these services may not function properly.

  • Targeting cookies

    They may be set through our site by our advertising partners, to build a profile of your interests and to show you relevant adverts on other sites. They do not store directly personal information, but are based on uniquely identifying your browser and internet device. If you do not allow these cookies, you will experience less targeted advertising.